Motif ID: TLX1..3_NFIC{dimer}.p2

Z-value: 1.011


Transcription factors associated with TLX1..3_NFIC{dimer}.p2:

Gene SymbolEntrez IDGene Name
TLX1 3195 T-cell leukemia homeobox 1
TLX3 30012 T-cell leukemia homeobox 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TLX1chr10_+_1028910600.183.3e-01Click!
TLX3chr5_+_1707362870.077.3e-01Click!


Activity profile for motif TLX1..3_NFIC{dimer}.p2.

activity profile for motif TLX1..3_NFIC{dimer}.p2


Sorted Z-values histogram for motif TLX1..3_NFIC{dimer}.p2

Sorted Z-values for motif TLX1..3_NFIC{dimer}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TLX1..3_NFIC{dimer}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_128788913 1.739 NM_017413
 APLN
apelin
chr11_-_71752099 1.392 NUMA1
nuclear mitotic apparatus protein 1
chr7_+_73624328 1.339 LAT2
linker for activation of T cells family, member 2
chr7_+_73624347 1.281 LAT2
linker for activation of T cells family, member 2
chr19_+_10397642 1.275 NM_001039132
NM_001544
NM_022377
 ICAM4


intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)


chr1_+_79086087 1.175 NM_006820
 IFI44L
interferon-induced protein 44-like
chr3_+_126261178 1.150 CHST13
carbohydrate (chondroitin 4) sulfotransferase 13
chr19_-_41356193 1.100 NM_000762
 CYP2A6
cytochrome P450, family 2, subfamily A, polypeptide 6
chr17_-_39143252 0.911 NM_182497
 KRT40
keratin 40
chr6_-_46922533 0.877 NM_015234
 GPR116
G protein-coupled receptor 116
chr1_-_205391180 0.854 NM_001001552
NM_001199050
NM_001199051
NM_001199052
 LEMD1



LEM domain containing 1



chr8_-_10512616 0.847 NM_178857
 RP1L1
retinitis pigmentosa 1-like 1
chr3_+_100328432 0.826 NM_032787
 GPR128
G protein-coupled receptor 128
chr17_-_3182267 0.825 NM_002551
 OR3A2
olfactory receptor, family 3, subfamily A, member 2
chr7_+_73624086 0.756 NM_014146
NM_032463
NM_032464
 LAT2


linker for activation of T cells family, member 2


chr19_+_15783827 0.733 NM_023944
 CYP4F12
cytochrome P450, family 4, subfamily F, polypeptide 12
chr5_-_73937248 0.732 NM_003633
 ENC1
ectodermal-neural cortex 1 (with BTB-like domain)
chrX_-_53310748 0.721 NM_001243197
NM_015075
 IQSEC2

IQ motif and Sec7 domain 2

chr17_+_48503607 0.715 ACSF2
acyl-CoA synthetase family member 2
chr14_+_24540742 0.700 NM_006032
 CPNE6
copine VI (neuronal)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
17.57 2.36e-02 GO:0048755 branching morphogenesis of a nerve
1.49 2.48e-02 GO:0009653 anatomical structure morphogenesis
1.48 4.80e-02 GO:0009966 regulation of signal transduction
1.43 1.78e-02 GO:0048583 regulation of response to stimulus
1.36 4.09e-03 GO:0048731 system development
1.35 1.46e-03 GO:0048856 anatomical structure development
1.32 9.96e-04 GO:0032502 developmental process
1.32 2.96e-03 GO:0007275 multicellular organismal development
1.23 6.80e-03 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
2.36 9.14e-05 GO:0005578 proteinaceous extracellular matrix
2.24 7.74e-05 GO:0031012 extracellular matrix
2.15 5.15e-03 GO:0015629 actin cytoskeleton
1.97 7.97e-03 GO:0009986 cell surface
1.85 2.43e-07 GO:0044421 extracellular region part
1.72 1.13e-03 GO:0005615 extracellular space
1.50 1.29e-05 GO:0005576 extracellular region
1.42 3.61e-04 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
12.55 5.85e-03 GO:0034713 type I transforming growth factor beta receptor binding
1.55 1.96e-02 GO:0005102 receptor binding